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Advances in Psychiatric Treatment (2005) 11: 38-44
© 2005 The Royal College of Psychiatrists

First-episode schizophrenia: review of cognitive deficits and cognitive remediation

Y. Vishnu Gopal and Hannele Variend

Vishnu Gopal is a final-year specialist registrar in Sheffield (Hartington Unit for Psychiatry, Royal Hospital, Chesterfield S44 5BL, UK. E-mail: vgopal{at}doctors.org.uk). His areas of interests include working with patients with disorders of memory, psychopharmacological treatments, early intervention and home treatment. Hannele Variend is a senior house officer in psychiatry on the Sheffield rotation and has interests in early-onset psychosis.

The presence of cognitive deficits in schizophrenic illness has been extensively documented, and deficits in memory and executive functioning may be related to poor prognosis. Targeting these deficits during the early phase has potential benefits. The neural basis for cognitive deficits in schizophrenia is not well understood, and hence pharmacological interventions alone are insufficient. Future strategies should focus on pharmacological interventions combined with psychological techniques such as cognitive remediation. This review summarises recent findings relating to first-episode schizophrenia.




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