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Advances in Psychiatric Treatment (2005) 11: 195-202
© 2005 The Royal College of Psychiatrists

Neuroimaging in schizophrenia: what does it tell the clinician?

James Woolley and Philip McGuire

James Woolley is a clinical research fellow at the Institute of Psychiatry and an honorary specialist registrar at the Maudsley Hospital, London (Section of Neuroimaging, PO67, Institute of Psychiatry, Denmark Hill, London SE5 8AF, UK. Tel: 020 7848 0369; fax: 020 7848 0956; j.woolley{at}iop.kcl.ac.uk). His research interests include neuroimaging in obsessive–compulsive disorder and early psychosis, and clinical interventions to reduce the impact of pre-psychotic symptoms. Philip McGuire is Professor of Psychiatry and Cognitive Neuroscience and Head of the Section of Neuroimaging at the Institute of Psychiatry, London. His research is focused on neurocognitive processes that are putatively defective in psychosis. He is also Clinical Director of Outreach and Support in South London (OASIS) and of the Voices Clinic, Maudsley Hospital, and an honorary consultant to the Lambeth Early Onset (LEO) service.

Neuroimaging has been used in clinical practice for over 30 years, but it is still perceived as rarely offering the psychiatrist much help in direct patient management. As newer imaging modalities are introduced (from computed tomography and positron and single photon emission tomography to magnetic and functional magnetic resonance imaging), the promise of imminent clinical utility is reawakened, only to fade as the innovation is shown to be another, albeit useful, research tool. The aim of this article is to update readers on some recent advances that are starting to align the research and clinical functions of neuroimaging. As imaging becomes more accessible and affordable there is real promise that both clinicians and patients will begin to benefit more directly.




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