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Misuse of amphetamines and related drugs

Published online by Cambridge University Press:  02 January 2018

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This article discusses the misuse of drugs which act as stimulants, an effect mainly produced by enhancement of the central transmission of catecholamines, particularly dopamine. Stimulant misuse is extremely widespread in the UK and elsewhere, but primary users of such drugs present relatively rarely for treatment at drug services. At present such services mainly see heroin users, not only because the greater addictiveness of heroin produces generally higher levels of problems, but because a substitute treatment can be used in that group in the form of methadone.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists 1996 

References

De Jong, C. A. J., Van Den Brink, W., Harteveld, F. M. et al (1993) Personality disorders in alcoholics and drug addicts. Comprehensive Psychiatry, 34, 8794.Google Scholar
Department of Health (1995) Statistical Bulletin: Drug Misuse Statistics 1995/24. London: HMSO.Google Scholar
Gawin, F. H. & Kleber, H. D. (1986) Abstinence symptomatology and psychiatric diagnoses in cocaine abusers: clinical observations. Archives of General Psychiatry, 43, 107113.Google Scholar
Henry, J. A., Jeffreys, K. J. & Dawling, S. (1992) Toxicity and deaths from 3, 4-methylenedioxymethamphetamine ('ecstasy'). Lancet, 340, 384387.Google Scholar
Holman, R. B. (1994) Biological effects of central nervous system stimulants. Addiction, 89, 14351441.Google Scholar
Institute for the Study of Drug Dependence (1994) Drug Misuse in Britain. London: ISDD.Google Scholar
Levin, F. R. & Lehman, A. F. (1991) Meta-analysis of desipramine as an adjunct in the treatment of cocaine addiction. Journal of Clinical Psychopharmacology, 11, 374378.Google Scholar
Lipton, D. S., Brewington, V. & Smith, M. (1994) Acupuncture for crack-cocaine detoxification: experimental evaluation of efficacy. Journal of Substance Abuse Treatment, 11, 205215.Google Scholar
McGuire, P. K., Cope, H. & Fahy, T. A. (1994) Diversity of psychopathology associated with use of 3, 4-methylenedioxymethamphetamine ('Ecstasy'). British Journal of Psychiatry, 165, 391395.Google Scholar
Milroy, C. M., Clark, J. C. & Forrest, A. R. W. (1996) Pathology of deaths associated with “ecstasy” and “eve” misuse. Journal of Clinical Pathology, 49, 149153.Google Scholar
Peroutka, S. J., Newman, H. & Harris, H. (1988) Subjective effects of 3,4-methylenedixoymethamphetamine in recreational users. Neuropsychopharmacology, 1, 273277.Google Scholar
Poison, R. G., Fleming, P. M. & O'Shea, J. K. (1993) Fluoxetine in the treatment of amphetamine dependence. Human Psychopharmacology, 8, 5558.Google Scholar
Poole, R. & Brabbins, C. (1996) Drug induced psychosis. British Journal of Psychiatry, 168, 135138.Google Scholar
Steele, T. D., McCann, T. D. & Ricaurte, G. A. (1994) 3, 4-methylenedioxymethamphetamine (MDMA, “ecstasy”): pharmacology and toxicology in animals and humans. Addiction, 89, 539551.Google Scholar
Strang, J., Griffiths, P. & Gossop, M. (1990) Crack and cocaine use in South London drug addicts: 1987–1989. British Journal of Addiction, 85, 193196.Google Scholar
Weddington, W. W., Brown, B. S., Haertzen, C. A. et al (1990) Changes in mood, craving, and sleep during short-term abstinence reported by male cocaine addicts. Archives of General Psychiatry, 47, 861868.Google Scholar
Withers, N. W., Pulvirenti, L., Koob, G. F. et al (1995) Cocaine abuse and dependence. Journal of Clinical Psychopharmacology, 15, 6378.Google Scholar
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